Paradox Immunotherapeutics

Problem

Protein misfolding diseases and amyloidosis can result in multi-organ failure

When proteins in your body fail to form to their proper shape, they can lose their intended function.

These misfolded proteins form aggregated clumps or insoluble amyloid fibrils.

These toxic deposits can disrupt the natural activities in tissues and organs, causing disease.

There are over 30 different types of protein misfolding diseases such as ALS (Lou Gehrig's Disease), Alzheimer’s and Parkinson’s Disease, as well as a rare subset of diseases called Amyloidosis

Lack of Available Therapeutics

Only 8% of rare diseases have FDA approved therapeutics

Prevalent Disease Across the Globe

Amyloidosis affects 300 people per million worldwide, with over 90,000 patients in the United States

There are many types of amyloidosis

The 3 most common forms are AL amyloidosis, ATTR amyloidosis and ALECT2 amyloidosis

Our Vision

Reshaping the future of protein misfolding diseases

The challenge of protein misfolding disease is targeting the often-scarce disease causing forms of the protein that cause disease, while avoiding the abundant, healthy form which performs important roles needed by your body. Because of this, many protein misfolding diseases are very difficult to manage and are currently thought of as incurable. Paradox is ready to change that.

OUR PIPELINE

The paradox Advantage

Empowering the immune system with the tools to combat rare protein misfolding diseases

Paradox has a proven-successful drug design platform that allows them to identify and develop specialized antibodies that can selectively target only the problematic/misfolded proteins while leaving the healthy proteins in your body untouched.

We know how to develop transformative therapeutics.

Providing hope for protein misfolding diseases.

A rockstar scientific team.

A proven-successful drug design platform.

We know how to develop transformative therapeutics.

A rockstar scientific team.

Providing hope for protein misfolding diseases.